Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061712 | 0.87 | CYP1A2 (0.84) | CYP1A2HIF1A | |
| SCHEMBL1011715 | 0.77 | CYP1A2 (0.89) | CYP1A2HIF1A | |
| SCHEMBL7248550 | 0.77 | TDP1 (0.44) | CYP1A2HIF1ATDP1MAPK1 | |
| SCHEMBL18648961 | 0.67 | TDP1 (0.55) | CYP1A2HIF1ATDP1POLBTSHR | |
| SCHEMBL7652967 | 0.66 | CYP2C19 (0.46) | POLBTSHRCHRM2CHRM4 | |
| SCHEMBL14490104 | 0.66 | MEN1 (0.44) | CYP1A2HIF1ATDP1MAPTPOLB | |
| SCHEMBL1333467 | 0.65 | CYP2D6 (0.35) | CYP1A2HIF1ATSHR | |
| SCHEMBL21322442 | 0.65 | CYP1A2 (0.59) | CYP1A2HIF1A | |
| SCHEMBL30702633 | 0.65 | CYP1A2 (0.59) | CYP1A2HIF1A | |
| SCHEMBL12019480 | 0.64 | CYP1A2 (0.34) | CYP1A2HIF1ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486323-B1 | Process for producing optically active tropinonemonocarboxylic acid derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-11-26 | — | — | US | disclosed |