Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247464 | 0.83 | SLC6A4 (0.43) | CYP2C19TSHRCYP3A4KMT2ASLC6A4 | |
| SCHEMBL1011983 | 0.83 | SLC6A4 (0.54) | CYP3A4ALDH1A1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL1010837 | 0.82 | FKBP1A (0.47) | TSHRALDH1A1SLC6A3 | |
| SCHEMBL1011753 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1SLC6A4POLB | |
| SCHEMBL1010278 | 0.80 | SLC6A4 (0.43) | TSHRCYP3A4ALDH1A1KMT2ASLC6A4 | |
| SCHEMBL11097065 | 0.78 | SLC6A4 (0.48) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL11095157 | 0.78 | SLC6A4 (0.48) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL1010262 | 0.77 | L3MBTL1 (0.43) | TSHRCYP3A4ALDH1A1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11093298 | 0.76 | CHRM2 (0.49) | SLC6A4SLC6A3CHRM2CHRM4CHRM5 | |
| SCHEMBL4710677 | 0.75 | GRM6 (0.49) | TSHRS1PR1S1PR5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486323-B1 | Process for producing optically active tropinonemonocarboxylic acid derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-11-26 | — | — | US | disclosed |