Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649363 | 0.99 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7648097 | 0.99 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7653213 | 0.97 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7650240 | 0.96 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7652681 | 0.94 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7649416 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7654242 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7656027 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL7653344 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL15345301 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |