Butyrolactone

Butyrolactone

SCHEMBL7650673

CC(C)=O.O=C1CCCO1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.64
CA9 Q16790 1/20 0.64
LMNA P02545 3/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C9 P11712 1/20 0.35
CYP2D6 P10635 1/20 0.33
PGR P06401 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrolactone SCHEMBL10999881 0.93 CA1 (0.61) CA1CA9LMNAALDH1A1TP53
Acetone SCHEMBL27767208 0.91 CA1 (0.73) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL21611328 0.90
Butyrolactone SCHEMBL25327385 0.89 CA1 (0.56) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL7686323 0.87 CA1 (0.67) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL25427151 0.87 CA1 (0.67) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL2821176 0.87 CA1 (0.54) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL5439842 0.87 CA1 (0.54) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL1271043 0.87 CA1 (0.82) CA1CA9LMNAALDH1A1TP53
Butyrolactone SCHEMBL29433925 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527156-B1 HIGHLY CONDUCTIVE POLYMER THICK FILM COMPOSITIONS ACHESON IND INC (US) 1996-07-31 EP claimed
US-5389263-A Use of superciritical fluids and gases as anti-solvents; purification PHASEX CORPORATION (US) 1995-02-14 US claimed
US-6475496-B1 Gelled cosmetic remover composition REVLON CONSUMER PRODUCTS CORPORATION 2002-11-05 US disclosed