Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646280 | 0.92 | SLC7A5 (0.43) | L3MBTL1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL25048209 | 0.88 | RCE1 (0.44) | L3MBTL1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7647703 | 0.84 | MRGPRX4 (0.40) | LPAR1L3MBTL1HDAC1MRGPRX4HDAC3 | |
| SCHEMBL5464169 | 0.82 | FOLH1 (0.47) | MRGPRX4AKR1C3 | |
| SCHEMBL2797220 | 0.81 | HDAC3 (0.47) | L3MBTL1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL30563213 | 0.80 | CA14 (0.45) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL25378075 | 0.80 | CA14 (0.45) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4717431 | 0.80 | LTB4R (0.36) | HDAC1HDAC3HDAC2NCOR2RCE1 | |
| SCHEMBL14415230 | 0.79 | SLC7A5 (0.51) | SLC7A5 | |
| SCHEMBL19078990 | 0.79 | MAPT (0.45) | L3MBTL1HDAC1MRGPRX4HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |