Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.51 |
| ▸ | MMP9 | P14780 | 9/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.51 |
| ▸ | MMP13 | P45452 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628372 | 0.89 | MMP1 (0.49) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7505855 | 0.89 | MMP1 (0.48) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7551349 | 0.87 | MAPT (0.46) | MMP1MMP9ADAM17MMP13MAPT | |
| SCHEMBL19066004 | 0.84 | MMP1 (0.50) | MMP1MMP9ADAM17MMP13MAPT | |
| SCHEMBL7515447 | 0.83 | MMP1 (0.47) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7618341 | 0.82 | MMP1 (0.50) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7569299 | 0.78 | MMP1 (0.52) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7625228 | 0.78 | MMP1 (0.44) | MMP1MMP9ADAM17MMP13MMP3 | |
| SCHEMBL7513095 | 0.77 | KMT2A (0.47) | MMP1MMP9ADAM17MMP13MAPT | |
| SCHEMBL7594294 | 0.77 | MMP1 (0.55) | MMP1MMP9ADAM17MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462073-B2 | METALLOPROTEASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION | 2002-10-08 | — | — | US | disclosed |