Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952783 | 0.85 | EDNRB (0.56) | EDNRB | |
| SCHEMBL7952339 | 0.74 | EDNRB (0.43) | EDNRB | |
| SCHEMBL7943855 | 0.72 | — | — | |
| SCHEMBL7954478 | 0.72 | — | — | |
| SCHEMBL7956971 | 0.70 | EDNRB (0.45) | EDNRB | |
| SCHEMBL7943839 | 0.70 | — | — | |
| SCHEMBL7943811 | 0.69 | EDNRB (0.58) | EDNRB | |
| SCHEMBL7956808 | 0.67 | — | — | |
| SCHEMBL7952065 | 0.66 | — | — | |
| SCHEMBL7944035 | 0.63 | EDNRB (0.38) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479671-B1 | Process for producing optically active chromene derivative | SHIONOGI & CO., LTD. (JP) | 2002-11-12 | — | — | US | disclosed |
| EP-1057824-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |