Isopropylbenzene

Isopropylbenzene

SCHEMBL7651432

CC(C)C(C)c1ccccc1.CC(C)c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.43
AOC3 Q16853 1/20 0.40
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599878 0.92 TAAR1 (0.48) TAAR1AOC3ADRA2AADRA2CCYP2D6
SCHEMBL19519886 0.92 TAAR1 (0.48) TAAR1AOC3ADRA2AADRA2CCYP2D6
Ammonia Solution, Strong SCHEMBL7513659 0.89 TAAR1 (0.46) TAAR1AOC3ADRA2AADRA2CCYP2D6
SCHEMBL17748822 0.86 TYR (0.46) CYP2D6LMNAHIF1AKDM4EALDH1A1
Isopropylbenzene SCHEMBL8431863 0.86 TAAR1 (0.50) TAAR1ADRA2AADRA2CCYP2D6LMNA
Isopropylbenzene SCHEMBL6568 0.86
Isopropylbenzene SCHEMBL3672803 0.86 TAAR1 (0.50) TAAR1ADRA2AADRA2CCYP2D6LMNA
Isopropylbenzene SCHEMBL87809 0.86 TAAR1 (0.50) TAAR1ADRA2AADRA2CCYP2D6LMNA
Isopropylbenzene SCHEMBL11254813 0.86
Isopropylbenzene SCHEMBL23421101 0.83 ADRA2C (0.52) TAAR1ADRA2AADRA2CCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020133043-A1 Method for production of oxygen-containing aromatic compound NIPPON SHOKUBAI CO., LTD. (JP) 2002-09-19 US disclosed