SCHEMBL7651476

SCHEMBL7651476

O=C(O)c1c(C(F)(F)F)c(F)c(F)c2c(F)c(F)c(F)c(F)c12

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076184 0.85 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMEN1KMT2AGPR35
SCHEMBL7653550 0.81
SCHEMBL7650893 0.80 THRB (0.31)
SCHEMBL7656603 0.79 THRB (0.32)
SCHEMBL27956970 0.78 SMN1; SMN2 (0.41) SMN1; SMN2TSHRMEN1KMT2AGPR35
SCHEMBL7656590 0.78 THRB (0.34)
SCHEMBL10606616 0.78 SMN1; SMN2 (0.48) SMN1; SMN2TSHRMEN1KMT2AGPR35
SCHEMBL27700963 0.78 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMEN1KMT2AGPR35
SCHEMBL7718847 0.78 TSHR (0.34) SMN1; SMN2TSHR
SCHEMBL3202669 0.77 MEN1 (0.37) SMN1; SMN2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US claimed
US-3989843-A Emulsification of fluorocarbon compounds for biological application as oxygen transporters PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-11-02 US claimed
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US disclosed
US-3989843-A Emulsification of fluorocarbon compounds for biological application as oxygen transporters PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-11-02 US disclosed