Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651495 | 1.00 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7659658 | 0.94 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7659653 | 0.94 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7653068 | 0.94 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7653881 | 0.88 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7657917 | 0.84 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL9544682 | 0.83 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL7534415 | 0.78 | EDNRB (0.54) | EDNRAEDNRB | |
| SCHEMBL7999632 | 0.77 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7652001 | 0.76 | EDNRA (0.50) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355813-B1 | INTERMEDIATES USEFUL IN PREPARING THESE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2002-03-12 | — | — | US | disclosed |
| US-6143907-A | 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |