Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657917 | 0.93 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7653068 | 0.88 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7653881 | 0.84 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7651495 | 0.83 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7651503 | 0.83 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7659658 | 0.79 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7659653 | 0.79 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7534415 | 0.75 | EDNRB (0.54) | EDNRAEDNRB | |
| SCHEMBL7999632 | 0.73 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL8624509 | 0.73 | EDNRA (0.44) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008799-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |