SCHEMBL7651535

SCHEMBL7651535

O=S(=O)(O)CCC(O)S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15674185 0.84 APP (0.44) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL9289667 0.82 CA5A (0.33)
SCHEMBL30446754 0.80 APP (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL30336502 0.80 APP (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL23501717 0.79 CA5A (0.31)
SCHEMBL1695401 0.79 CA5A (0.31)
SCHEMBL1819524 0.77
SCHEMBL13937392 0.77 TP53 (0.31)
SCHEMBL14641422 0.74 PTGS1 (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL28795920 0.74 PTGS1 (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108697604-A DEPILATORY COMPOSITIONS 雷克特本克斯尔(品牌)有限公司 2018-10-23 CN claimed
CN-108697604-A DEPILATORY COMPOSITIONS 雷克特本克斯尔(品牌)有限公司 2018-10-23 CN disclosed
EP-1181361-A2 OLIGONUCLEOTIDE DERIVATIVES DIRECTED AGAINST HUMAN BCL-XL AND HUMAN BCL-2 MRNA Universität Zürich (CH) 2002-02-27 EP disclosed
WO-2000066724-A2 OLIGONUCLEOTIDE DERIVATIVES DIRECTED AGAINST HUMAN BCL-XL AND HUMAN BCL-2 MRNA Universität Zürich (CH) 2000-11-09 WO disclosed