Biphenyl

Biphenyl

SCHEMBL7651806

CCCCCCCCCCCCCCCCCCN[Ti](C1=C(C)C(C)=C(C)C1C)[SiH](c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 4/20 0.31
NAAA Q02083 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
SOAT2 O75908 2/20 0.30
SIGMAR1 Q99720 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
STAT1 P42224 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7654337 1.00 SOAT1 (0.31) SOAT1NAAAHRH4HRH3SOAT2
Biphenyl SCHEMBL7650294 1.00 SOAT1 (0.31) SOAT1NAAAHRH4HRH3SOAT2
SCHEMBL822593 0.96 NAAA (0.33) NAAASIGMAR1ALDH1A1
SCHEMBL6062030 0.96 NAAA (0.33) NAAASIGMAR1ALDH1A1
SCHEMBL822663 0.96 NAAA (0.33) NAAASIGMAR1ALDH1A1
Biphenyl SCHEMBL7649000 0.88 SOAT1 (0.32) SOAT1NAAAHRH4HRH3SOAT2
Biphenyl SCHEMBL7655380 0.88 SOAT1 (0.32) SOAT1NAAAHRH4HRH3SOAT2
Biphenyl SCHEMBL7650994 0.88 SOAT1 (0.32) SOAT1NAAAHRH4HRH3SOAT2
SCHEMBL7108087 0.86 NAAA (0.35) NAAASIGMAR1ALDH1A1
SCHEMBL861805 0.86 NAAA (0.35) NAAASIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423795-B1 USING COORDINATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. 2002-07-23 US disclosed
US-RE37788-E1 Monocyclopentadienyl metal compounds for ethylene-α-olefin-copolymer production catalysts EXXON CHEMICAL PATENTS, INC. 2002-07-09 US disclosed
US-5621126-A METAL COMPLEX WITH CYCLOPENTADIENE CONTAINS AN AMIDO GROUP HAVING ALIPHATIC OR ALICYCLIC HYDROCARBYL GROUP COVALENTLY BONDED THERETO THROUGH A PRIMARY OR SECONDARY CARBON ATOM; USED AS POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS INC. (US) 1997-04-15 US disclosed