⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15403020 | 1.00 | — | — | |
| SCHEMBL15402452 | 0.92 | — | — | |
| SCHEMBL1470105 | 0.81 | — | — | |
| SCHEMBL15403247 | 0.81 | — | — | |
| SCHEMBL31682370 | 0.81 | MMP2 (0.31) | — | |
| SCHEMBL31682369 | 0.81 | MMP2 (0.34) | — | |
| SCHEMBL15403347 | 0.80 | — | — | |
| SCHEMBL1470194 | 0.75 | — | — | |
| SCHEMBL15404123 | 0.74 | — | — | |
| SCHEMBL15402931 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014140241-A1 | PYRIDINE DERIVATIVES AS DGAT-1 INHIBITORS | INTERVET INTERNATIONAL B.V. (NL) | 2014-09-18 | — | — | WO | disclosed |
| WO-2012112364-A1 | LACTAM DERIVATIVES AS DGAT-1 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-08-23 | — | — | WO | disclosed |
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |