Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22834331 | 0.80 | APP (0.71) | MAPTNPC1APPCYP2A6MEN1 | |
| SCHEMBL19369179 | 0.78 | MAPT (0.55) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL16552630 | 0.78 | CYP2D6 (0.58) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL12208049 | 0.77 | CYP2A6 (0.50) | MAPTAPPCYP2A6MEN1KMT2A | |
| SCHEMBL16552798 | 0.77 | NR5A1 (0.58) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL13309870 | 0.77 | NR5A1 (0.58) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL2396650 | 0.75 | NR5A1 (0.56) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL3791496 | 0.75 | NR5A1 (0.56) | MAPTRAB9ANPC1CYP2D6CYP3A4 | |
| SCHEMBL12231917 | 0.75 | CYP2A6 (0.54) | MAPTRAB9ANPC1CYP2D6APP | |
| SCHEMBL7648176 | 0.74 | RAB9A (0.55) | MAPTRAB9ANPC1CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530338-B1 | ANISOTROPIC ORGANIC COMPOUNDS | QINETIQ LTD (GB) | 2002-05-02 | — | — | EP | disclosed |
| US-5888421-A | LIQUID CRYSTALS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1999-03-30 | — | — | US | disclosed |
| WO-1992016519-A2 | ANISOTROPIC ORGANIC COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-10-01 | — | — | WO | disclosed |