Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088635 | 0.94 | TACR1 (0.61) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7085266 | 0.94 | TACR1 (0.62) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7656874 | 0.93 | TACR1 (0.61) | TACR1MAPTP2RY14MEN1POLB | |
| SCHEMBL7089795 | 0.93 | TACR1 (0.59) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7088170 | 0.93 | TACR1 (0.69) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7089245 | 0.93 | TACR1 (0.68) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7090514 | 0.92 | TACR1 (0.58) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7088789 | 0.92 | TACR1 (0.62) | TACR1MAPTP2RY14MEN1POLB | |
| SCHEMBL7087794 | 0.92 | TACR1 (0.62) | TACR1MAPTP2RY14LMNATP53 | |
| SCHEMBL7088018 | 0.92 | TACR1 (0.62) | TACR1MAPTP2RY14MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358994-B1 | 2-((2-PHENOXY)ACETYL)AMINO-3-(1H-INDOL-3-YL)-1-(N-2 -METHOXYBENZYL)ACETYLAMINO)PROPANE | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |