Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649384 | 0.95 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2HRH3 | |
| SCHEMBL7652630 | 0.94 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2HRH3HTR2A | |
| SCHEMBL7650154 | 0.91 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL7654532 | 0.84 | SLC6A3 (0.71) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL5089817 | 0.81 | SLC6A3 (0.77) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5085799 | 0.81 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5086438 | 0.78 | SLC6A4 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3517653 | 0.78 | SLC6A3 (1.00) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15862743 | 0.76 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL3516027 | 0.74 | SLC6A3 (1.00) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |