Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654606 | 0.87 | PPARG (0.61) | PPARGPTPN1PTGER4PDE2APDE10A | |
| SCHEMBL7660302 | 0.78 | PPARG (0.50) | PPARGPTPN1PTGER4SCN9A | |
| SCHEMBL7651510 | 0.78 | PPARG (0.69) | PPARGPTPN1 | |
| SCHEMBL1160303 | 0.77 | PPARG (0.82) | PPARGPTPN1PTGER4IRAK4 | |
| SCHEMBL6134720 | 0.77 | PPARG (0.80) | PPARGPTPN1PTGER4 | |
| SCHEMBL1160144 | 0.77 | PPARG (0.81) | PPARGPTPN1PTGER4IRAK4 | |
| SCHEMBL1160346 | 0.77 | PPARG (0.81) | PPARGPTPN1PTGER4IRAK4 | |
| SCHEMBL1160232 | 0.75 | PPARG (0.78) | PPARGPTGER4IRAK4 | |
| SCHEMBL1160011 | 0.75 | PPARG (0.65) | PPARGPTPN1 | |
| SCHEMBL7657036 | 0.74 | PPARG (0.46) | PPARGPDE2APDE10AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420409-B1 | GLUCOSE TOLERANCE, DIABETES,INSULIN RESISTANCE, POLYCYSTIC OVARY SYNDROME, HYPERLIPIDEMIA, ATHEROSCLEROSIS, CARDIOVASCULAR DISORDERS, HYPERGLYCEMIA, HYPERTENSION, STENOCARDIA, PULMONARY HYPERTENSION, CONGESTIVE HEART FAILURE, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1020452-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |