Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654606 | 0.78 | PPARG (0.61) | PPARGIRAK4TP53PDE2APDE10A | |
| SCHEMBL7650797 | 0.77 | PPARG (0.59) | PPARGIRAK4PDE2APDE10A | |
| SCHEMBL7652356 | 0.76 | PPARG (0.64) | PPARGIRAK4 | |
| SCHEMBL6304040 | 0.75 | PPARG (0.64) | PPARGIRAK4 | |
| SCHEMBL7652173 | 0.74 | PPARG (0.56) | PPARGIRAK4PDE2APDE10A | |
| SCHEMBL6308682 | 0.74 | PPARG (0.66) | PPARGIRAK4TP53MEN1KMT2A | |
| SCHEMBL6303336 | 0.73 | PPARG (0.63) | PPARGIRAK4 | |
| SCHEMBL7656313 | 0.72 | PPARG (0.77) | PPARGIRAK4TP53MEN1KMT2A | |
| SCHEMBL6308426 | 0.71 | PPARG (0.65) | PPARGIRAK4TP53 | |
| SCHEMBL6301645 | 0.71 | PPARG (0.65) | PPARGIRAK4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380223-B1 | FOR THERAPY OF DISEASES, SUCH AS OBESITY, DIABETES, INFLAMMATION | PFIZER INC. | 2002-04-30 | — | — | US | disclosed |