SCHEMBL7652189

SCHEMBL7652189

C(=Cc1ccccc1-c1ccccc1N=Nc1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
NFE2L2 Q16236 4/20 0.42
TRPA1 O75762 2/20 0.42
ALDH1A1 P00352 2/20 0.40
NQO2 P16083 1/20 0.38
SIGMAR1 Q99720 2/20 0.36
MEN1 O00255 3/20 0.34
MAPK1 P28482 3/20 0.34
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NR1H2 P55055 1/20 0.34
CYP3A4 P08684 2/20 0.33
MAOB P27338 2/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805506 0.86 NFE2L2 (0.47) CASP3SENP8SENP7SENP6NFE2L2
Methane SCHEMBL27583285 0.84 NFE2L2 (0.46) CASP3SENP8SENP7SENP6NFE2L2
SCHEMBL14690301 0.81 NQO2 (0.47) NFE2L2TRPA1ALDH1A1NQO2SIGMAR1
SCHEMBL14690304 0.81 NQO2 (0.47) NFE2L2TRPA1ALDH1A1NQO2SIGMAR1
SCHEMBL14690303 0.81 NQO2 (0.47) NFE2L2TRPA1ALDH1A1NQO2SIGMAR1
SCHEMBL28399996 0.80 NFE2L2 (0.60) NFE2L2TRPA1MEN1KMT2AMAOB
SCHEMBL30130338 0.80 NFE2L2 (0.60) NFE2L2TRPA1MEN1KMT2AMAOB
SCHEMBL29567711 0.80 NFE2L2 (0.60) NFE2L2TRPA1MEN1KMT2AMAOB
SCHEMBL19031413 0.80 NFE2L2 (0.60) NFE2L2TRPA1MEN1KMT2AMAOB
SCHEMBL39008 0.80 NFE2L2 (0.60) NFE2L2TRPA1MEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1229099-C Use of reactive dyes for dyeing hair BASF AG (DE) 2005-11-30 CN disclosed
CN-1104472-C Reactive dyes with heterocyclic anchor BASF AG (DE) 2003-04-02 CN disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
CN-1072235-C Process for preparing dyed melamine-formaldehyde condensation products BASF AG (DE) 2001-10-03 CN disclosed
US-6197941-B1 TRIAZINE, METALLIZED, AZO, ANTHRAQUINONE, FORMAZAN, PHTHALOCYANINE, AND DIOXAZINE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
US-6159250-A Doubled reactive dyes BASF AKTIENGESELLSCHAFT (DE) 2000-12-12 US disclosed
CN-1264284-A Application of reactive dye in hair dyeing BASF AG (DE) 2000-08-23 CN disclosed
EP-1000123-A2 USE OF REACTIVE DYES FOR DYEING HAIR BASF AKTIENGESELLSCHAFT (DE) 2000-05-17 EP disclosed
CN-1239493-A Reactive dyes with heterocyclic anchor points BASF AG (DE) 1999-12-22 CN disclosed
US-5929217-A FOR DYEING OR PRINTING SUBSTRATES HAVING HYDROXYL GROUPS OR NITROGEN ATOMS BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 US disclosed
EP-0929610-A1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR BASF AKTIENGESELLSCHAFT (DE) 1999-07-21 EP disclosed
WO-1999005222-A2 USE OF REACTIVE DYES FOR DYEING HAIR BASF AKTIENGESELLSCHAFT (DE) 1999-02-04 WO disclosed
US-5837013-A Preparation of colored melamine-formaldehyde condensation products BASF AKTIENGESELLSCHAFT (DE) 1998-11-17 US disclosed
WO-1998014522-A1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR BASF AKTIENGESELLSCHAFT (DE) 1998-04-09 WO disclosed
CN-1171122-A Method for producing colored melamine-formaldehyde polycondensates BASF AG (DE) 1998-01-21 CN disclosed
US-5624466-A DYEING FIBERS, KNITS, NONWOVENS WITH AZO, ANTHRAQUINONE, COUMARIN, METHINE, QUINOPHTHALONE OR NITRO DYES BASF AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed
US-5245020-A Reactive dyes with two or three nitrogen-containing haloheterocycles as reactive system BASF AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
US-5241055-A Use in cold pad-batch processing; fixing; fiber bonding; color- and washfastness; monoazo-, disazo-formazan, triphenyldioxazine and metal phthalocyanine dyes BASF AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
US-5231171-A Dyeing or printing substrates such as cellulose BASF AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5149789-A Triazine dyes BASF AKTIENGESELLSCHAFT (DE) 1992-09-22 US disclosed