SCHEMBL6927738

SCHEMBL6927738

CCCCCC(C)(C)c1ccc(Nc2ccc(CCCC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.47
HPGD P15428 6/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
POLB P06746 1/20 0.41
UNG P13051 3/20 0.41
PLK1 P53350 1/20 0.41
CASP3 P42574 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SENP8 Q96LD8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39060 0.90 CNR2 (0.54) CNR2
SCHEMBL6932062 0.90 CNR2 (0.43) CNR2HPGDSMN1; SMN2MAPTALDH1A1
SCHEMBL502238 0.85 CNR2 (0.50) CNR2
SCHEMBL501958 0.84 CNR2 (0.49) CNR2HPGDSMN1; SMN2MAPTALDH1A1
SCHEMBL7652240 0.83 HPGD (0.50) HPGDNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL14390805 0.83 CNR2 (0.48) CNR2
SCHEMBL14419136 0.83 CNR2 (0.48) CNR2
SCHEMBL14127779 0.81 HPGD (0.58) HPGDNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL48879 0.81 HPGD (0.58) HPGDNPC1RAB9ASMN1; SMN2MAPT
SCHEMBL258169 0.79 ESR1 (0.59) HPGDSMN1; SMN2MAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
EP-1023377-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-08-02 EP claimed
WO-1999016821-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
WO-1996012760-A2 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-05-02 WO disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed