Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.50 |
| ▸ | PDE4A | P27815 | 18/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7991157 | 0.82 | PDE4B (0.67) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7652196 | 0.81 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7354104 | 0.71 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7991274 | 0.71 | PDE4D (0.57) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7378679 | 0.70 | PDE4D (0.57) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6229674 | 0.67 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7657365 | 0.67 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7584180 | 0.65 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7654903 | 0.65 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7359292 | 0.64 | PDE4A (0.48) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003105815-A1 | COMBINATION OF PDE-V INHIBITORS AND NK1 ANTAGONISTS FOR THE TREATMENT OF DEPRESSION | PFIZER PRODUCTS INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |