Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27348674 | 0.94 | KDM4E (0.62) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| Piperazine SCHEMBL5309240 | 0.94 | KDM4E (0.72) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| Morpholine SCHEMBL27773497 | 0.92 | KDM4E (0.57) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| SCHEMBL28846659 | 0.90 | ALDH1A1 (0.57) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| SCHEMBL12958951 | 0.90 | KDM4E (0.73) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| SCHEMBL416345 | 0.89 | SMN1; SMN2 (0.50) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| Hydrochloric Acid SCHEMBL27141329 | 0.87 | GLA (0.48) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| SCHEMBL19177427 | 0.87 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL25262333 | 0.87 | KDM4E (0.90) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 | |
| SCHEMBL13758294 | 0.87 | KDM4E (0.90) | KDM4EALDH1A1GLASMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469214-B2 | ETHANOLAMINE(S), OPTIONALLY IN THE PRESENCE OF AMMONIA, IS/ARE TREATED WITH A STRONG BASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | claimed |