SCHEMBL7652848

SCHEMBL7652848

CCc1ccc(CCc2cc(F)c3c(c2)CC(C)C3)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
GPR84 Q9NQS5 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064836 0.81 HTR1D (0.31)
SCHEMBL7062971 0.75 HTR2C (0.33) GPR84PTGS1PTGS2DRD2DRD3
SCHEMBL7061283 0.69 NR3C2 (0.31) DRD2DRD3
SCHEMBL21386525 0.69 NOTUM (0.32)
SCHEMBL14098860 0.67
SCHEMBL8454840 0.65 TAAR1 (0.37) TAAR1GPR84L3MBTL1
SCHEMBL8454839 0.65 TAAR1 (0.37) TAAR1GPR84L3MBTL1
SCHEMBL6546733 0.64 TAAR1 (0.68) TAAR1GPR84L3MBTL1LMNA
SCHEMBL24997114 0.64 CTSD (0.42) DRD2DRD3
SCHEMBL7062989 0.64 CYP3A4 (0.37) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6485797-B1 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2002-11-26 US disclosed
EP-1027403-A2 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME Aventis Research & Technologies GmbH & Co. KG (DE) 2000-08-16 EP disclosed
WO-1999019420-A2 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-22 WO disclosed