Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654737 | 0.98 | CNR2 (0.38) | LIPGMAPTCNR2CNR1CYP3A4 | |
| SCHEMBL7653475 | 0.92 | CNR2 (0.39) | LIPGCNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL7649388 | 0.86 | LIPG (0.48) | LIPGALOX5THRATHRB | |
| SCHEMBL7655901 | 0.84 | CNR2 (0.40) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL7648157 | 0.84 | LIPG (0.46) | LIPGALOX5THRATHRB | |
| SCHEMBL7650731 | 0.84 | CYP1A2 (0.46) | LIPGMAPTCNR2CYP3A4ALDH1A1 | |
| SCHEMBL11779245 | 0.82 | LIPG (0.57) | LIPGMAPTCNR2CYP3A4KDM4E | |
| SCHEMBL30537736 | 0.82 | LIPG (0.57) | LIPGMAPTCNR2CYP3A4KDM4E | |
| SCHEMBL30537733 | 0.82 | KDM4E (0.46) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL798769 | 0.82 | KDM4E (0.46) | CNR2CNR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |