Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC3R | P41968 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600348 | 1.00 | GHSR (0.46) | GHSRMMP9MMP8PSMB5MC4R | |
| SCHEMBL6602015 | 0.88 | GHSR (0.43) | GHSR | |
| SCHEMBL6602009 | 0.88 | GHSR (0.43) | GHSR | |
| SCHEMBL6600352 | 0.85 | GHSR (0.42) | GHSRMMP9PSMB5 | |
| SCHEMBL6600521 | 0.85 | GHSR (0.39) | GHSR | |
| SCHEMBL3730171 | 0.82 | GHSR (0.48) | GHSRMMP9MMP8PSMB5 | |
| SCHEMBL3730166 | 0.82 | GHSR (0.48) | GHSRMMP9MMP8PSMB5 | |
| SCHEMBL3730165 | 0.82 | GHSR (0.48) | GHSRMMP9MMP8PSMB5 | |
| SCHEMBL3794280 | 0.82 | GHSR (0.48) | GHSRMMP9MMP8PSMB5 | |
| SCHEMBL3794277 | 0.82 | GHSR (0.48) | GHSRMMP9MMP8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | claimed |
| EP-0907374-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997046252-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1997-12-11 | — | — | WO | disclosed |