Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27718102 | 0.98 | ALDH1A1 (0.63) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL21059179 | 0.89 | MEN1 (0.65) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3998159 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL9356687 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL16667717 | 0.85 | TSHR (0.61) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL28230483 | 0.85 | TP53 (0.54) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL5881193 | 0.85 | TSHR (0.66) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL5137574 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL9363696 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL17078097 | 0.83 | TSHR (0.63) | ALDH1A1TSHRGLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669095-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9326976-B2 | Carbamate derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-05-03 | — | — | US | disclosed |
| US-20150352090-A1 | CARBAMATE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-10 | — | — | US | disclosed |
| CN-1424999-A | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-06-18 | — | — | CN | disclosed |
| WO-2002072025-A2 | IMPROVING POSTSYNAPTIC RESPONSE BY A COMBINATION OF 4-MINOPYRIDINE AND AGONIST | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2002-09-19 | — | — | WO | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352090-A1 | CARBAMATE DERIVATIVES | CHRM3, PDE4A, PDE4B | ALDH1A1 1060/4885TSHR 345/4885GLA 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.