Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064802 | 1.00 | MRGPRX4 (0.35) | MRGPRX4SMYD3TRPM8HSP90AA1HSP90AB1 | |
| SCHEMBL7062211 | 1.00 | MRGPRX4 (0.35) | MRGPRX4SMYD3TRPM8HSP90AA1HSP90AB1 | |
| SCHEMBL7063409 | 0.80 | HSP90AA1 (0.35) | MRGPRX4HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL7063406 | 0.80 | HSP90AA1 (0.35) | MRGPRX4HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL6806719 | 0.79 | HSP90AA1 (0.35) | TRPM8HSP90AA1HSP90AB1S1PR1S1PR3 | |
| SCHEMBL6806711 | 0.79 | HSP90AA1 (0.35) | TRPM8HSP90AA1HSP90AB1S1PR1S1PR3 | |
| SCHEMBL7058680 | 0.78 | KDM4E (0.35) | HSP90AA1HSP90AB1CCNCCDK8MEN1 | |
| SCHEMBL7058684 | 0.78 | KDM4E (0.35) | HSP90AA1HSP90AB1CCNCCDK8MEN1 | |
| SCHEMBL7255762 | 0.78 | KDM4E (0.35) | HSP90AA1HSP90AB1CCNCCDK8MEN1 | |
| SCHEMBL7062208 | 0.77 | ELANE (0.35) | MRGPRX4HSP90AA1HSP90AB1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137961-A1 | Resorcinol derivatives | PFIZER INC. | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137961-A1 | Resorcinol derivatives | LRAT, NQO1, ALDH1A2 | MRGPRX4 790/4885SMYD3 2788/4885TRPM8 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.