Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.66 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112377 | 0.89 | TPSAB1 (0.61) | LSSTPSAB1HTR7HTR6F10 | |
| SCHEMBL8121856 | 0.86 | LSS (0.57) | LSSTPSAB1ALDH1A1HTR7HTR6 | |
| SCHEMBL7662786 | 0.86 | LSS (0.53) | LSSTPSAB1L3MBTL1ALDH1A1HTR7 | |
| SCHEMBL7956164 | 0.85 | LSS (0.70) | LSSL3MBTL1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7651857 | 0.84 | LSS (0.50) | LSSTPSAB1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8120701 | 0.82 | TPSAB1 (0.74) | LSSTPSAB1ALDH1A1HTR7HTR6 | |
| SCHEMBL7662833 | 0.81 | TP53 (0.62) | LSSL3MBTL1 | |
| SCHEMBL8124161 | 0.81 | F10 (0.69) | TPSAB1HTR7HTR6F10 | |
| SCHEMBL7401658 | 0.80 | LSS (1.00) | LSSL3MBTL1SMN1; SMN2F10MAPK1 | |
| SCHEMBL8121200 | 0.78 | TPSAB1 (0.62) | LSSTPSAB1HTR7HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |