Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855567 | 1.00 | CHRM2 (0.37) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL6855572 | 1.00 | CHRM2 (0.37) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL6861146 | 0.83 | CHRM2 (0.33) | CHRM2CHRM1CHRM3SLC1A2HRH3 | |
| SCHEMBL6863810 | 0.78 | SLC1A2 (0.48) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL10581821 | 0.78 | SLC1A2 (0.48) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL24039255 | 0.78 | MAPK1 (0.37) | CHRM2CHRM1CHRM3SLC1A2HRH3 | |
| SCHEMBL678255 | 0.78 | SLC1A2 (0.48) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL16417261 | 0.78 | SLC1A2 (0.48) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL5728913 | 0.77 | MAPK1 (0.37) | CHRM2CHRM1CHRM3SLC1A2HRH3 | |
| SCHEMBL2677786 | 0.76 | CHRM2 (0.35) | CHRM2CHRM1CHRM3SLC1A2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237862-A1 | SUCCINATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE AND PREPARATION | Versicor, Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044179-A1 | NOVEL SUCCINATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE AND PREPARATION | VERSICOR, INC. (US) | 2001-06-21 | — | — | WO | disclosed |