SCHEMBL678255

SCHEMBL678255

CC(=O)OC1CCN[C@@H]1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.48
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
BLM P54132 1/20 0.41
CHRM2 P08172 5/20 0.39
CHRM1 P11229 3/20 0.39
CHRM4 P08173 2/20 0.39
CHRM3 P20309 2/20 0.39
CYP2D6 P10635 1/20 0.38
ARG1 P05089 4/20 0.38
ARG2 P78540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16417261 1.00 SLC1A2 (0.48) SLC1A2MEN1KMT2ABLMCHRM2
SCHEMBL6863810 1.00 SLC1A2 (0.48) SLC1A2MEN1KMT2ABLMCHRM2
SCHEMBL10581821 1.00 SLC1A2 (0.48) SLC1A2MEN1KMT2ABLMCHRM2
SCHEMBL11771633 0.86 SLC1A2 (0.41) SLC1A2MEN1KMT2ABLMCHRM2
SCHEMBL3333748 0.82 SLC1A2 (0.43) SLC1A2MEN1KMT2ABLMARG1
SCHEMBL10680722 0.80 SLC1A2 (0.52) SLC1A2MEN1KMT2ABLMARG1
SCHEMBL7348716 0.80 SLC1A2 (0.52) SLC1A2MEN1KMT2ABLMARG1
SCHEMBL7346916 0.80 SLC1A2 (0.52) SLC1A2MEN1KMT2ABLMARG1
SCHEMBL7280336 0.80 SLC1A2 (0.52) SLC1A2MEN1KMT2ABLMARG1
Hydrochloric Acid SCHEMBL26117737 0.78 SLC1A2 (0.50) SLC1A2MEN1KMT2ABLMARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US claimed
EP-2789341-A2 O-acetylated amino acids as anti-platelet agents and nutritional supplements Chandran, V. Ravi (US) 2014-10-15 EP claimed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US claimed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US claimed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US claimed
EP-1957066-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS Chandran, V. Ravi (US) 2008-08-20 EP claimed
WO-2007059047-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS CHANDRAN V RAVI (US) 2007-05-24 WO claimed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US claimed
US-3932638-A Compositions and methods for wound healing FRANCO-CHIMIE S.A.R.L. (FR) 1976-01-13 US claimed
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
EP-2789341-A2 O-acetylated amino acids as anti-platelet agents and nutritional supplements Chandran, V. Ravi (US) 2014-10-15 EP disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0307390-A2 Chemical compound consisting of cis-3-hydroxyproline for therapeutic treatment, and process for its preparation MERCKLE GMBH (DE) 1989-03-15 EP disclosed
US-4772284-A Breast prosthesis with improved biocompatibility and method of making the same COLLAGENIX CORPORATION (US) 1988-09-20 US disclosed
US-3997559-A N-acetyl-L-hydroxy-proline zinc salt FRANCO CHIMIE S.A.R.L. (FR) 1976-12-14 US disclosed
US-3932638-A Compositions and methods for wound healing FRANCO-CHIMIE S.A.R.L. (FR) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC1A2 919/4885MEN1 3872/4885KMT2A 1202/4885
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS PLTP, GP6, PDGFA SLC1A2 919/4885MEN1 3872/4885KMT2A 1202/4885
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements PLTP, GP6, PDGFA SLC1A2 919/4885MEN1 3872/4885KMT2A 1202/4885
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC1A2 919/4885MEN1 3872/4885KMT2A 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.