SCHEMBL7653725

SCHEMBL7653725

CCOc1ccc2c(ccc3cc(F)ccc32)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1A P35813 2/20 0.54
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NQO1 P15559 1/20 0.45
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
CYP1A2 P05177 3/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
CYP11B1 P15538 2/20 0.42
CYP11B2 P19099 2/20 0.42
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363683 0.93 NQO1 (0.52) PPM1AMAPTNQO1AKR1C3AKR1C2
SCHEMBL18417197 0.89 NQO1 (0.56) PPM1AMAPTALDH1A1HSD17B10NQO1
SCHEMBL12259987 0.87 NQO1 (0.54) PPM1AMAPTALDH1A1HSD17B10NQO1
SCHEMBL7658803 0.86 PPM1A (0.56) PPM1AHSD17B10CA12CA1CA4
SCHEMBL7662625 0.86 PPM1A (0.50) PPM1AMAPTALDH1A1HSD17B10CYP1A2
SCHEMBL12269044 0.85 NQO1 (0.52) PPM1AMAPTALDH1A1HSD17B10NQO1
SCHEMBL7656268 0.83 PPM1A (0.54) PPM1ACA12CA1CA4CA6
SCHEMBL7668477 0.82 PPM1A (0.53) PPM1ACA12CA1CA4CA6
SCHEMBL29629327 0.80 NQO1 (0.68) MAPTALDH1A1HSD17B10NQO1AKR1C3
SCHEMBL3825385 0.80 NQO1 (0.68) MAPTALDH1A1HSD17B10NQO1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495220-B2 WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS CLARIANT INTERNATIONAL LTD. (CH) 2002-12-17 US disclosed
US-20010023935-A1 With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers CLARIANT INTERNATIONAL LTD. (CH) 2001-09-27 US disclosed