SCHEMBL7653853

CC(=O)N[C@@H](Cc1ccc(OCC(=O)O)c(OCC(=O)O)c1)C(=O)N[C@H]1CCCCc2cc(OCC3CCCCC3)c(C(N)=O)cc21

nearest known ligand 0.76

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	SRC	P12931	17/20	0.76

▸	YES1	P07947	2/20	0.58

▸	PTPN1	P18031	1/20	0.41

▸	MEN1	O00255	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7657834	0.94	SRC (0.73)	SRCYES1PTPN1MEN1KMT2A
SCHEMBL7674065	0.93	SRC (0.80)	SRCYES1
SCHEMBL7657787	0.93	SRC (0.85)	SRCYES1PTPN1
SCHEMBL7653010	0.89	SRC (0.82)	SRCYES1
SCHEMBL7653013	0.89	SRC (0.82)	SRCYES1
SCHEMBL7654913	0.89	SRC (0.82)	SRCYES1
SCHEMBL7653006	0.89	SRC (0.82)	SRCYES1
SCHEMBL7781774	0.89	SRC (0.61)	SRCYES1PTPN1
SCHEMBL7243003	0.86	SRC (1.00)	SRCYES1
SCHEMBL9891649	0.86	SRC (1.00)	SRCYES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6482852-B2	UE TREATING PROLIFERATIVE DISEASE, CANCER, RESTENOSIS, OSTEOPOROSIS, INFLAMMATION, ALLERGIES, OR CARDIOVASCULAR DISEASE; INHIBITION OF SH2-MEDIATED SIGNALING	ARIAD PHARMACEUTICALS, INC.	2002-11-19	—	—	US	disclosed