SCHEMBL9891649

SCHEMBL9891649

CC(=O)NC(Cc1ccc(C(=O)O)c(C=O)c1)C(=O)NC1CCCCc2cc(OCC3CCCCC3)c(C(N)=O)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SRC P12931 19/20 1.00
YES1 P07947 2/20 0.48
PARP15 Q460N3 1/20 0.37
PARP10 Q53GL7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7243003 1.00 SRC (1.00) SRCYES1PARP15PARP10
SCHEMBL7657344 0.94 SRC (0.88) SRCYES1PARP15PARP10
SCHEMBL7653013 0.87 SRC (0.82) SRCYES1PARP15PARP10
SCHEMBL7654913 0.87 SRC (0.82) SRCYES1PARP15PARP10
SCHEMBL7653010 0.87 SRC (0.82) SRCYES1PARP15PARP10
SCHEMBL7653006 0.87 SRC (0.82) SRCYES1PARP15PARP10
SCHEMBL7653853 0.86 SRC (0.76) SRCYES1
SCHEMBL7674065 0.86 SRC (0.80) SRCYES1PARP15PARP10
SCHEMBL29432639 0.84 SRC (1.00) SRCYES1
SCHEMBL7245569 0.84 SRC (1.00) SRCYES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150369816-A1 Polypeptide Immobilization UNIV CHICAGO (US) 2015-12-24 US disclosed
US-9074300-B2 Polypeptide immobilization THE UNIVERSITY OF CHICAGO (US) 2015-07-07 US disclosed
US-20120142547-A1 POLYPEPTIDE IMMOBILIZATION THE UNIVERSITY OF CHICAGO 2012-06-07 US disclosed
EP-2311939-A1 Polypeptide immobilization The University of Chicago (US) 2011-04-20 EP disclosed
US-7888055-B2 Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity THE UNIVERSITY OF CHICAGO (US) 2011-02-15 US disclosed
US-7888055-B2 Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity THE UNIVERSITY OF CHICAGO (US) 2011-02-15 US disclosed
US-20080064606-A1 Polypeptide immobilization THE UNIVERSITY OF CHICAGO 2008-03-13 US disclosed
US-20080064606-A1 Polypeptide immobilization THE UNIVERSITY OF CHICAGO 2008-03-13 US disclosed
US-7172905-B2 Polypeptide immobilization THE UNIVERSITY OF CHICAGO (US) 2007-02-06 US disclosed
US-7172905-B2 Polypeptide immobilization THE UNIVERSITY OF CHICAGO (US) 2007-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064606-A1 Polypeptide immobilization QPCTL, SURF4, QPCT SRC 761/4885YES1 1401/4885PARP15 1079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.