Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.67 |
| ▸ | HRH1 | P35367 | 2/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675738 | 0.93 | HRH3 (0.68) | HRH3KCNH2HRH1 | |
| SCHEMBL7653222 | 0.92 | HRH3 (0.68) | HRH3KCNH2HRH1 | |
| SCHEMBL7653368 | 0.92 | HRH3 (0.68) | HRH3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL7653978 | 0.86 | HRH3 (0.70) | HRH3KCNH2HRH1HRH2HRH4 | |
| SCHEMBL12050718 | 0.85 | HRH3 (0.96) | HRH3KCNH2HRH1HRH2HRH4 | |
| SCHEMBL12050645 | 0.83 | HRH3 (1.00) | HRH3KCNH2HRH1HRH2HRH4 | |
| SCHEMBL4094339 | 0.83 | HRH3 (1.00) | HRH3KCNH2HRH1HRH2HRH4 | |
| SCHEMBL7006365 | 0.83 | HRH3 (0.76) | HRH3KCNH2HRH1HRH2 | |
| SCHEMBL4098597 | 0.82 | HRH3 (0.84) | HRH3KCNH2HRH1HRH2ACHE | |
| SCHEMBL7682850 | 0.81 | CA12 (0.70) | HRH3KCNH2HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |