Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | SDHA | P31040 | 2/20 | 0.55 |
| ▸ | CALML3 | P27482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539861 | 1.00 | MAOA (0.55) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7545733 | 0.90 | MAOA (0.58) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL6797071 | 0.86 | MAOA (0.66) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7547274 | 0.85 | MAOA (0.57) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7545047 | 0.84 | MAOA (0.60) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7608522 | 0.83 | MAOA (0.53) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7608500 | 0.83 | MAOA (0.53) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7539446 | 0.83 | MAOA (0.58) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7606959 | 0.82 | MAOA (0.52) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7608700 | 0.82 | MAOA (0.52) | MAOAMAOBPTGS1SDHACALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410728-B1 | BACTERICIDES; PSORIASIS; ANTIARTHRITIC AGENTS; TREATING TOXICITY DUE TO CHEMOTHERAPY; OBESITY; ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS, MORAXELLA, ENTEROCOCCUS AND STREPTOCOCCUS; GRAMPOSITIVE BACTERIA | ABBOTT LABORATORIES | 2002-06-25 | — | — | US | disclosed |