Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.59 |
| ▸ | NPC1 | O15118 | 11/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663231 | 0.92 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7662602 | 0.91 | RAB9A (0.66) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7651939 | 0.87 | KMT2A (0.55) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL926117 | 0.86 | MAPT (0.64) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7655740 | 0.85 | KDM4E (0.72) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7652753 | 0.85 | MEN1 (0.55) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7665040 | 0.84 | MAPT (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7666772 | 0.83 | NPC1 (0.64) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7660111 | 0.83 | RAB9A (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7852156 | 0.83 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |