Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167975 | 0.94 | GBA1 (0.47) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL6167695 | 0.89 | GBA1 (0.53) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL594600 | 0.79 | GBA1 (0.61) | GBA1CCR3CARM1PRMT6PRMT3 | |
| SCHEMBL316482 | 0.79 | GBA1 (0.65) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL7812033 | 0.79 | GBA1 (0.54) | GBA1CCR3CARM1PRMT6PRMT3 | |
| SCHEMBL8701 | 0.79 | GBA1 (0.65) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL28738028 | 0.78 | CTSL (0.47) | — | |
| SCHEMBL6290794 | 0.77 | GBA1 (0.63) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL158625 | 0.77 | GBA1 (0.63) | GBA1CCR3SLC18A3CARM1PRMT6 | |
| SCHEMBL8137977 | 0.77 | GBA1 (0.63) | GBA1CCR3SLC18A3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |