Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746148 | 0.78 | MAPT (0.62) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| SCHEMBL30822838 | 0.78 | MAPT (0.62) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| SCHEMBL28657003 | 0.77 | MAPT (0.53) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| SCHEMBL6679985 | 0.77 | CYP2D6 (0.51) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28652075 | 0.76 | MAPT (0.50) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| SCHEMBL31103641 | 0.74 | MEN1 (0.76) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1572442 | 0.74 | MEN1 (0.76) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3388760 | 0.73 | NPC1 (0.62) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| SCHEMBL5869531 | 0.73 | MAPT (0.62) | ADRB2ADRB1ADRB3MAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL27704150 | 0.73 | MEN1 (0.74) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |