Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652075 | 0.84 | MAPT (0.50) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL30822838 | 0.84 | MAPT (0.62) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL4746148 | 0.84 | MAPT (0.62) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL27461038 | 0.79 | MAPT (0.52) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL14636054 | 0.78 | TDP1 (0.50) | MAPTALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL27384308 | 0.77 | MAPT (0.50) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL7654085 | 0.77 | ADRB2 (0.53) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29868333 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL3913255 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1CES2CES1MEN1 | |
| SCHEMBL27479603 | 0.76 | ALDH1A1 (0.58) | MAPTALDH1A1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113544113-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113544113-A | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2021-10-22 | — | — | CN | disclosed |