SCHEMBL7654154

SCHEMBL7654154

CC1(c2cccc3ccccc23)C(=O)N(CCCn2ccnc2)C(=O)N1C(=O)N1CCOCC1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.60
FNTB P49356 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7654184 0.85 FNTA (0.70) FNTAFNTB
SCHEMBL7657797 0.82 FNTA (0.69) FNTAFNTB
SCHEMBL7652866 0.79 FNTA (0.64) FNTAFNTB
SCHEMBL7652739 0.76 FNTA (0.62) FNTAFNTB
SCHEMBL7651908 0.76 FNTA (0.88) FNTAFNTB
SCHEMBL7656649 0.74 FNTA (1.00) FNTAFNTB
SCHEMBL7658647 0.74 FNTA (0.84) FNTAFNTB
SCHEMBL7660503 0.74 FNTA (0.75) FNTAFNTB
SCHEMBL7662335 0.74 FNTA (1.00) FNTAFNTB
SCHEMBL7662245 0.73 FNTA (0.69) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384061-B1 HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS LG CHEMICAL LTD. (KR) 2002-05-07 US claimed
US-6384061-B1 HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS LG CHEMICAL LTD. (KR) 2002-05-07 US disclosed