Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GCK | P35557 | 2/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18719858 | 0.76 | POLB (0.73) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL28478041 | 0.76 | POLB (0.73) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL1230760 | 0.74 | NPC1 (0.66) | RAB9ANPC1KMT2ALMNAPOLB | |
| SCHEMBL3559655 | 0.73 | MEN1 (0.60) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL10842534 | 0.71 | NPC1 (0.62) | RAB9ANPC1KMT2AMEN1POLB | |
| SCHEMBL8078718 | 0.70 | ABCG2 (0.76) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL8663226 | 0.70 | ABCG2 (0.76) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL2651868 | 0.70 | GCK (0.61) | KMT2ALMNAPOLBGCKPLA2G7 | |
| SCHEMBL2651866 | 0.70 | GCK (0.61) | KMT2ALMNAPOLBGCKPLA2G7 | |
| SCHEMBL7691923 | 0.70 | KMT2A (0.65) | KMT2AMEN1LMNAPOLBGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492394-B1 | PROCOLLAGEN C-PROTEINASE INHIBITORS; TREATING FIBROTIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-12-10 | — | — | US | disclosed |