SCHEMBL8078718

SCHEMBL8078718

O=C(C=Cc1cccs1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.76
MAPT P10636 9/20 0.73
HCAR2 Q8TDS4 1/20 0.68
RAB9A P51151 4/20 0.61
NPC1 O15118 2/20 0.61
CASP3 P42574 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
LMNA P02545 7/20 0.59
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
ALDH1A1 P00352 3/20 0.59
ATM Q13315 1/20 0.59
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
SMN1; SMN2 Q16637 3/20 0.56
POLB P06746 1/20 0.56
RECQL P46063 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663226 1.00 ABCG2 (0.76) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL11477087 0.90 ABCG2 (0.77) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL11477089 0.90 ABCG2 (0.77) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL17429547 0.86 ABCG2 (1.00) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL28708176 0.86 ABCG2 (1.00) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL3035766 0.85 ABCG2 (0.74) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL31301136 0.85 ABCG2 (0.74) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL7203615 0.85 MAPT (1.00) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL7203616 0.85 MAPT (1.00) ABCG2MAPTHCAR2RAB9ANPC1
SCHEMBL3035768 0.85 ABCG2 (0.74) ABCG2MAPTHCAR2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240261768-A1 POLYNORBORNENE/CARBON BLACK-CROSS-LINKED THREE-DIMENSIONAL NETWORK-IMMOBILIZED COPPER/GOLD (PNBI/CB-Cu/Au) NANOCATALYST, AND PREPARATION METHOD AND USE THEREOF Hubei Engineering University (CN) 2024-08-08 US claimed
US-12576396-B2 Polynorbornene/carbon black-cross-linked three-dimensional network-immobilized copper/gold (PNBI/CB-Cu/Au) nanocatalyst, and preparation method and use thereof Hubei Engineering University (CN) 2026-03-17 US disclosed
US-20240261768-A1 POLYNORBORNENE/CARBON BLACK-CROSS-LINKED THREE-DIMENSIONAL NETWORK-IMMOBILIZED COPPER/GOLD (PNBI/CB-Cu/Au) NANOCATALYST, AND PREPARATION METHOD AND USE THEREOF Hubei Engineering University (CN) 2024-08-08 US disclosed
WO-2023206835-A1 CROSS-LINKED NORBORNENE COPOLYMER/CARBON BLACK THREE-DIMENSIONAL NETWORK IMMOBILIZED BIMETALLIC COPPER/GOLD NANO-CATALYST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北工程学院 2023-11-02 WO disclosed
CN-111925324-B Synthetic method of 3-acyl quinoline compound 南通大学 2022-07-29 CN disclosed
CN-111925324-A Synthetic method of 3-acyl quinoline compound 南通大学 2020-11-13 CN disclosed
US-20160145273-A1 PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2016-05-26 US disclosed
EP-1051910-A2 The treatment of pests using certain ethylenically-unsaturated carbonyl compounds Sorex Limited (GB) 2000-11-15 EP disclosed
EP-0662968-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1998-12-02 EP disclosed
EP-0662968-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-07-19 EP disclosed
EP-0662968-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS. PPG INDUSTRIES INC (US) 1995-04-12 EP disclosed
WO-1994007889-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1994-04-14 WO disclosed
US-5274132-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1993-12-28 US disclosed
US-5037824-A Cardiotonic, antiischemic agents FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-08-06 US disclosed
EP-0387070-A2 N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261768-A1 POLYNORBORNENE/CARBON BLACK-CROSS-LINKED THREE-DIMENSIONAL NETWORK-IMMOBILIZED COPPER/GOLD (PNBI/CB-Cu/Au) NANOCATALYST, AND PREPARATION METHOD AND USE THEREOF AOC3, PNN, RPL23A ABCG2 1186/4885MAPT 1563/4885HCAR2 3997/4885
US-12576396-B2 Polynorbornene/carbon black-cross-linked three-dimensional network-immobilized copper/gold (PNBI/CB-Cu/Au) nanocatalyst, and preparation method and use thereof AOC3, PNN, SOD3 ABCG2 1413/4885MAPT 1217/4885HCAR2 4204/4885
US-20160145273-A1 PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS TBCB, RUVBL2, RHEB ABCG2 3446/4885MAPT 1058/4885HCAR2 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.