Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.52 |
| ▸ | CTSS | P25774 | 12/20 | 0.52 |
| ▸ | CTSK | P43235 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 9/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061910 | 0.95 | CTSL (0.56) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL6741968 | 0.91 | CTSL (0.54) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL6737517 | 0.88 | CTSL (0.49) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL6741252 | 0.87 | CTSL (0.51) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL7664695 | 0.87 | ESRRG (0.52) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7667375 | 0.87 | CTSL (0.49) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL7666762 | 0.87 | CTSL (0.48) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL7655925 | 0.87 | CTSL (0.49) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6737869 | 0.87 | CTSL (0.48) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6740671 | 0.87 | CTSL (0.51) | CTSLCTSSCTSKCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |