Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.53 |
| ▸ | FNTB | P49356 | 10/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660388 | 0.98 | FNTA (0.56) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7669307 | 0.93 | FNTA (0.45) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7656231 | 0.92 | FNTA (0.49) | FNTAFNTBTDP1 | |
| SCHEMBL7667473 | 0.91 | FNTA (0.54) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8211342 | 0.91 | FNTA (0.42) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7660594 | 0.90 | CYP3A4 (0.43) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7656236 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7657896 | 0.88 | CYP51A1 (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7660347 | 0.88 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL7561152 | 0.87 | FNTA (0.51) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025089-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 2000-08-09 | — | — | EP | claimed |
| WO-1999020612-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-04-29 | — | — | WO | claimed |
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | disclosed |
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| EP-1025089-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999020612-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |