SCHEMBL7654349

SCHEMBL7654349

NC(CCP(=O)(O)OF)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.55
GRM8 O00222 2/20 0.53
GRM6 O15303 2/20 0.53
GRM4 Q14833 2/20 0.53
GRM7 Q14831 1/20 0.53
GCLC P48506 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3348058 0.81 GLUL (0.55) GLULGRM8GRM6GRM4GRM7
SCHEMBL5058494 0.81 GLUL (0.55) GLULGRM8GRM6GRM4GRM7
SCHEMBL21759002 0.81 GLUL (0.55) GLULGRM8GRM6GRM4GRM7
SCHEMBL20912924 0.81 GLUL (0.59) GLULGRM8GRM6GRM4GRM7
SCHEMBL31368621 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7
Ammonia Solution, Strong SCHEMBL31368625 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7
Ammonia Solution, Strong SCHEMBL16394029 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7
Ammonia Solution, Strong SCHEMBL16394030 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7
Potassium SCHEMBL31368624 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7
Hydrochloric Acid SCHEMBL28581658 0.79 GLUL (0.58) GLULGRM8GRM6GRM4GRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002028869-A1 GAMMA-GLUTAMYL TRANSPEPTIDASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH (US) 2002-04-11 WO disclosed