Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 11/20 | 0.48 |
| ▸ | FNTB | P49356 | 11/20 | 0.46 |
| ▸ | NRAS | P01111 | 1/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656642 | 0.89 | FNTA (0.55) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL7662015 | 0.74 | FNTA (0.51) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL7661101 | 0.73 | FNTA (0.43) | FNTAPGGT1BFNTB | |
| SCHEMBL8113945 | 0.72 | FNTA (0.42) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL6610051 | 0.69 | FNTA (0.54) | FNTAPGGT1BFNTBCYP11B1CYP11B2 | |
| SCHEMBL7967527 | 0.68 | FNTA (0.44) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL6599130 | 0.66 | FNTA (0.52) | FNTAPGGT1BFNTB | |
| SCHEMBL7651861 | 0.65 | FNTA (0.53) | FNTAFNTB | |
| SCHEMBL14416143 | 0.65 | CYP11B1 (0.59) | CYP11B1CYP11B2 | |
| SCHEMBL7663653 | 0.64 | FNTA (0.56) | FNTAPGGT1BFNTBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384061-B1 | HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS | LG CHEMICAL LTD. (KR) | 2002-05-07 | — | — | US | claimed |
| US-6384061-B1 | HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS | LG CHEMICAL LTD. (KR) | 2002-05-07 | — | — | US | disclosed |