Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648088 | 0.94 | CYP1A2 (0.48) | CYP1A2CYP2A6DAOSLC16A3ALDH1A1 | |
| SCHEMBL7650731 | 0.93 | CYP1A2 (0.46) | CYP1A2CYP2A6DAOSLC16A3ALDH1A1 | |
| SCHEMBL7653968 | 0.88 | CYP1A2 (0.54) | CYP1A2CYP2A6DAOSLC16A3ALDH1A1 | |
| SCHEMBL11070744 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP2A6DAOALDH1A1CNR2 | |
| SCHEMBL7653475 | 0.82 | CNR2 (0.39) | ALDH1A1CNR2 | |
| SCHEMBL27455037 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1CNR2CYP3A4 | |
| SCHEMBL14394642 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2A6DAOALDH1A1SLC6A4 | |
| SCHEMBL2454747 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP2A6DAOALDH1A1CYP3A4 | |
| SCHEMBL7653734 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2A6DAOALDH1A1CNR2 | |
| SCHEMBL7654737 | 0.77 | CNR2 (0.38) | ALDH1A1CNR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |