Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 8/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455037 | 0.94 | CYP1A2 (0.50) | CYP1A2CNR2CYP2A6TYRCNR1 | |
| SCHEMBL30537734 | 0.89 | CNR2 (0.48) | CNR2TYRLIPGTLR8 | |
| SCHEMBL8823285 | 0.89 | CNR2 (0.48) | CNR2TYRLIPGTLR8 | |
| SCHEMBL7831677 | 0.88 | CYP1A2 (0.52) | CYP1A2CNR2CYP2A6LIPGALDH1A1 | |
| SCHEMBL7653734 | 0.88 | CYP1A2 (0.56) | CYP1A2CNR2CYP2A6DAOCNR1 | |
| SCHEMBL27512700 | 0.85 | CYP1A2 (0.41) | CYP1A2CNR2TYRDAOLIPG | |
| SCHEMBL3677393 | 0.83 | LIPG (0.53) | CNR2TYRLIPGKDM4EALDH1A1 | |
| SCHEMBL22100016 | 0.83 | BCHE (0.43) | CYP1A2 | |
| SCHEMBL14394642 | 0.82 | CYP1A2 (0.50) | CYP1A2CYP2A6DAOKDM4EALDH1A1 | |
| SCHEMBL7654607 | 0.82 | CYP1A2 (0.50) | CYP1A2CNR2CYP2A6DAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465757-A | PYRIDINE STABILIZERS | CIBA-GEIGY A.G. (CH) | 1984-08-14 | — | — | US | disclosed |
| US-4060519-A | POLY(OXYALKYLENE)-POLYESTER-POLY(MONOSULFIDE) POLYTHIOL, NAPHTHALENE, CURING | PHILLIPS PETROLEUM COMPANY (US) | 1977-11-29 | — | — | US | disclosed |