Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.97 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 2/20 | 0.51 |
| ▸ | PYGM | P11217 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710025 | 0.87 | MLLT1 (0.79) | MLLT1SMYD3ALDH1A1KDM4EPDPK1 | |
| SCHEMBL21490044 | 0.87 | MLLT1 (0.79) | MLLT1SMYD3ALDH1A1KDM4EPDPK1 | |
| SCHEMBL14817861 | 0.86 | MLLT1 (0.76) | MLLT1SMYD3ALDH1A1KDM4EPDPK1 | |
| SCHEMBL17209748 | 0.84 | MLLT1 (0.70) | MLLT1SMYD3HPGDRAB9A | |
| SCHEMBL763943 | 0.84 | SMYD3 (0.77) | MLLT1SMYD3PYGL | |
| SCHEMBL11888227 | 0.84 | MLLT1 (0.70) | MLLT1SMYD3LMNAHPGDCYP2C19 | |
| SCHEMBL17209759 | 0.84 | MLLT1 (0.70) | MLLT1SMYD3LMNAHPGDCYP2C19 | |
| SCHEMBL17209760 | 0.84 | MLLT1 (0.70) | MLLT1SMYD3LMNAHPGDCYP2C19 | |
| SCHEMBL3610530 | 0.84 | MLLT1 (0.73) | MLLT1SMYD3ALDH1A1KDM4EPDPK1 | |
| SCHEMBL3610534 | 0.84 | MLLT1 (0.73) | MLLT1SMYD3ALDH1A1KDM4EPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270557-B1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |